BDBM50018011 Aubagio::CHEBI:68540::HMR-1726::TERIFLUNOMIDE

SMILES C\C(O)=C(/C#N)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=UTNUDOFZCWSZMS-YFHOEESVSA-N

Data  23 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50018011   

TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)
Affinity DataIC50:  388nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed